Back to Conditions

Iron Deficiency

Insufficient iron stores in the body, which can lead to anemia and various symptoms affecting energy and cognition.

Medical Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment.

Overview

Iron deficiency is the most common nutritional deficiency worldwide, affecting an estimated 2 billion people. Iron is essential for hemoglobin production, oxygen transport, energy metabolism, and cognitive function.

Iron deficiency progresses through stages: first, iron stores (ferritin) deplete; then circulating iron falls; finally, hemoglobin drops causing anemia. Many people have iron deficiency without anemia, experiencing symptoms like fatigue, brain fog, and hair loss.

Women of reproductive age are at highest risk due to menstrual blood loss. Other risk factors include pregnancy, vegetarian/vegan diets, GI conditions affecting absorption, and chronic blood loss.

Common Symptoms

  • •Fatigue and weakness
  • •Pale skin and nail beds
  • •Shortness of breath
  • •Dizziness
  • •Hair loss
  • •Brittle nails
  • •Restless legs syndrome
  • •Brain fog and difficulty concentrating
  • •Headaches
  • •Cold hands and feet
  • •Pica (cravings for ice, dirt, starch)
  • •Frequent infections

Key Blood Markers

Ferritin

Low (<30 μg/L indicates deficiency, <15 severe)

The most important marker - measures iron stores

Serum Iron

Low

Circulating iron - low confirms iron deficiency

Total Iron Binding Capacity

Elevated in iron deficiency

Increases when body needs more iron

Transferrin Saturation

Low (<20%)

Percentage of iron-binding sites occupied

Hemoglobin

Low if progressed to anemia

Falls in later stages when anemia develops

Frequently Asked Questions

What ferritin level is optimal?
While labs often list 15+ as normal, many experts consider optimal ferritin to be 50-100+ μg/L for best symptom resolution. Women with ferritin below 30 often have symptoms, even without anemia.
Why do women need more iron than men?
Menstrual blood loss depletes iron monthly. Women need 18mg of dietary iron daily vs 8mg for men. Heavy periods significantly increase requirements. This is why iron deficiency is 10x more common in women.
How long does it take to replenish iron stores?
Hemoglobin typically improves within 2-4 weeks of treatment. However, replenishing iron stores (normalizing ferritin) takes 3-6 months of continued supplementation. Don't stop when you feel better - complete the course.
What impairs iron absorption?
Coffee, tea, calcium, and antacids can reduce iron absorption by 50-90% if taken together. Take iron 2 hours apart from these. Vitamin C enhances absorption - take iron with orange juice or a vitamin C supplement.

Quick Facts

  • Key Markers:5
  • Common Symptoms:12

Recommended Panels

Related Conditions

Track Your Markers

Monitor Your Iron Deficiency Markers

Track the key biomarkers for iron deficiency over time. Upload your blood test results and see trends that matter.

Get Started FreeBrowse All Markers